Ageing determines a decrease of Hyaluronic Acid (HA), reduction of fibroblasts activity.
Aging and Hyaluronic Acid
Sunekos Performa is the latest innovation in aesthetic medicine research from Sunekos Laboratories.
It is composed of low molecular weight HA and the patented cluster of Amino Acids (AA), the HY6AA formula, in a new ratio “AA vs HA” allowing a significant reduction of the hyaluronidase action. [1;2;3;4]
A study on Sunekos Performa demonstrated that the presence of its specific combination of AAs (HY6AA formula), with their ancillary action, helps to decrease the degradation of HA by reducing the Hyaluronidase process. [1]
Therefore, the study suggests that Sunekos Performa, thanks to the new ratio “AA versus HA”, will persist longer and it will be more effective as the HA stimulation can last over an extended period. [1] [6]
Sunekos Performa helps to rebuild the Extra Cellular Matrix (ECM) in a more effective and complete way, by promoting the production of:
ECM model
Indication: wrinkles and skin laxity
Full Face
Periocular Area
Neck
Décolleté
Hands
“Sunekos Performa can also be used to treat periocular area, neck, décolleté and hands upon specific training with qualified personnel”
Studies
A study on Sunekos Performa demonstrated that the presence of its specific combination of AAs (HY6AA formula), with their ancillary action, helps to decrease the degradation of HA by reducing the Hyaluronidase process. [1]
Therefore, the study suggests that Sunekos Performa, thanks to the new ratio “AA versus HA”, will persist longer and it will be more effective as the HA stimulation can last over an extended period. [1] [6]
A study on ten patients on safety and efficacy of Sunekos Performa demonstrated that [6]
BEFORE AND AFTER
Courtesy by Elena Fasola
Courtesy by Elena Fasola
Courtesy by Mark Holmes
Courtesy by Elena Fasola
References
- Measurement of hyaluronidase activity on hyaluronic acid in presence or absence of a specific amino acid formula – Laura Tedesco and Enzo Nisoli [under publication]
- The role of hydrophobic modification on hyaluronic acid dynamics and self-assembly. Carbohydr Polym – Payne WM , Svechkarev D , Kyrychenko A , Mohs AM . 2018 Feb 15;182:132-141. doi: 10.1016/j.carbpol.2017.10.054
- Modified hyaluronic acid based materials for biomedical applications – Tiwari S , Bahadur P.. Int J Biol Macromol. 2019 Jan;121:556-571. doi: 10.1016/j.ijbiomac.2018.10.049.
- Sealing hyaluronic acid microgels with oppositely-charged polypeptides: A simple strategy for packaging hydrophilic drugs with on-demand release. – Labie H , Perro A , Lapeyre V , Goudeau B , Catargi B , Auzély R , Ravaine V. J Colloid Interface Sci. 2019 Feb 1;535:16-27. doi: 10.1016/j.jcis.2018.09.048
- Amino acid and hyaluronic acid mixtures differentially regulate extra cellular matrix genes in cultured human fibroblasts – B De Servi A Orlandini E Caviola M Meloni Biol Regul Homeost Agents. May-Jun 2018;32(3):517-527. PMID: 29921376)
- Pilot study evaluating the therapeutic effects of a new pre-mixed injectable product of low molecular weight (LMW)
hyaluronic acid added to six amino acids (HY6AA +Formula) in facial skin aging. – Fasola E, Kutera E. J Dermat Cosmetol.
2022;6(3):74-77